Relapse of multibacillary leprosy after treatment with daily rifampin plus ofloxacin for four weeks
To the Editor:
In a Letter to the Editor entitled "Relapse of multibacillary leprosy after rifampin and ofloxacin treatment for 28 days; a case report," published in the March 1998 issue of the INTERNATIONAL JOURNAL OF LEPROSY, Dr. R. Ganapati, el al. presented an excellent case report on a multibacillary patient who relapsed after treatment with daily rifampin plus ofloxacin for 28 days. However, their belief that it was the first case of relapse after treatment with the regimen was incorrect.
In collaborating with our colleagues from the Institut Marchoux, Bamako, Mali, we had observed a high relapse rate among lepromatous leprosy patients treated with the same regimen, and published the findings in the following article: Ji, B., Jamet, R, Sow, S., Perani, E. G., Traore, I. and Grosset, J. H. High relapse rate among lepromatous leprosy patients treated with rifampin plus ofloxacin daily for 4 weeks. Antimicrob. Agents Chemother. 41 (1997) 1953-1956. In fact, the abstract of this article was also published on page 81 of the same issue of IJL in which their correspondence was published.
- Baohong Ji, M.D.
Bactériologie et Hygiene
Faculté de Médecine Pitie-Salpetriere
91 Boulevard de l'Hôpital
75634 Paris, 13, France