%A Job CK %A Path FRC %A Truman RW %T Comparative study of mitsuda reaction to nude mouse and armadillo lepromin preparations using nine-banded armadillos %0 Journal Article %D 2000 %J International Journal of Leprosy and other Mycobacterial Diseases %P 0148-916X %V 68 %N 1 %X In 14 nine-banded armadillos the Mitsuda response to nude mouse-derived lepromin (lepromin-nu/nu) was compared to that of armadillo-derived lepromin (lepromin-A) by injecting the reagents intradermally into either side of the abdomen of the animal and examining the biopsies f rom the sites after 12 days. The histopathologic responses to both antigens were found to be similar, whether the animal was Milsudanegative (lepromatous) or Mitsuda-positivc (tuberculoid). It is pointed out that armadillos arc good experimental models for leprosy, and their use can replace humans in experimental studies.